Retinoic acid inducible gene-I mediated detection of bacterial nucleic acids in human microglial cells
Abstract Background Bacterial meningitis and meningoencephalitis are associated with devastating neuroinflammation.We and others have demonstrated the importance of glial cells in the initiation of immune responses to pathogens invading power cable the central nervous system (CNS).These cells use a variety of pattern recognition receptors (PRRs) to